NCT04290728

High-flow Nasal Oxygenation for Open Mouth

Effect of High-flow Nasal Oxygenation on Safe Apnea Time in Children With Open Mouth

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 10 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate the effect of high-flow nasal oxygenation on safe apnea time for children undergoing general anesthesia, with their mouth open.

Detailed description

Oxygenation via high-flow nasal cannula is gaining popularity in various clinical settings. It is known to increase apnea time for apneic patients including children. However, high-flow nasal cannula is known to be ineffective when the patient's mouth is kept open. When trying to intubate the patient during induction of anesthesia, the patient should be apneic with administration of neuromuscular blocking agent, and the mouth should be open for introduction of laryngoscope. We designed a prospective randomized controlled study to evaluate the effect of high-flow nasal oxygenation in the aforementioned setting for trying to intubate the patient.

Conditions

• Anesthesia, General
• Apnea

Interventions

Type	Name	Description
DEVICE	Apnea with high-flow nasal cannula	Application of oxygenation with high-flow nasal cannula with a rate of 2L/kg/min
OTHER	Apnea	Apnea without any application of oxygenation

Timeline

• Start date: 2020-04-16
• Primary completion: 2021-02-19
• Completion: 2021-02-19
• First posted: 2020-03-02
• Last updated: 2021-04-01

Locations

1 site across 1 country: South Korea

Regulatory

• FDA-regulated device study