Trials / Completed
CompletedNCT04285736
Efficacy of Oral Ivabradine in Patients Presenting With NSTEMI
The Efficacy of Oral Ivabradine in Patients Presenting With Acute Non ST-segment Elevation Myocardial Infarction (NSTEMI): Interventional Randomized Parallel Study
- Status
- Completed
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 100 (actual)
- Sponsor
- Cairo University · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to evaluate the beneficial effect of heart rate reduction of oral ivabradine in patients presenting with non ST-segment elevation myocardial infarction (NSTEMI) during acute stage post percutaneous coronary intervention versus conventional treatment. Materials and methods: A total of 100 patients admitted to the emergency department, National Heart Institute, Cairo, Egypt were randomized into two groups as follows: Group A: 50 patients with NSTEMI treated with ivabradine (5mg twice daily) in addition to the conventional treatment; Group B: 50 patients with NSTEMI treated with the conventional treatment only. Demographic data, detailed history, clinical examination, chest pain onset, blood pressure, heart rate (HR), temperature and respiratory rate, electrocardiogram (ECG) as well as echocardiography and laboratory investigations were recorded. Patients were monitored for a period of 3-5 days (acute stage).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ivabradine | Ivabradine (5mg twice daily) |
| DRUG | Conventional Treatment |
Timeline
- Start date
- 2014-12-01
- Primary completion
- 2016-05-01
- Completion
- 2016-05-01
- First posted
- 2020-02-26
- Last updated
- 2024-08-22
Source: ClinicalTrials.gov record NCT04285736. Inclusion in this directory is not an endorsement.