NCT04283916

Botulinum Toxin Injection in the Treatment of Open Abdomen

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: University of Oulu · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Botulinum toxin has been widely approved and utilized in the treatment of complex abdominal wall hernias. Botulinum toxin has been only randomly studied in the treatment of open abdomen.

Detailed description

30 consecutive patients who have open abdomen for any indication, will have 300 IU botulinum toxin injected in three spots in either sides of the abdomen within 72 hours of the start of open abdomen. The hypothesis is botulinum toxin relaxes abdominal wall musculature to ensure better and faster closure of the open abdomen.

Conditions

• Open Abdomen
• Botulinum Toxin Injection

Interventions

Type	Name	Description
DRUG	Botulinum Toxins	Botulinum toxin injection to abdominal wall

Timeline

• Start date: 2020-02-21
• Primary completion: 2024-06-01
• Completion: 2024-08-01
• First posted: 2020-02-25
• Last updated: 2024-02-01

Locations

1 site across 1 country: Finland

Regulatory

• FDA-regulated drug study