Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04280588

Fingolimod in COVID-19

Efficacy of Fingolimod in the Treatment of New Coronavirus Pneumonia (COVID-19)

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
First Affiliated Hospital of Fujian Medical University · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Although immune-inflammatory treatment is not routinely recommended to be used for SARS-CoV-2 pneumonia, according to the pathological findings of pulmonary oedema and hyaline membrane formation, timely and appropriate use of immune modulator together with ventilator support should be considered for the severe patients to prevent ARDS development. The sphingosine-1-phosphate receptor regulators Fingolimod (FTY720) is an effective immunology modulator which has been widely used in multiple sclerosis.The aim of this study was to determine whether the efficacy of fingolimod for a novel coronavirus disease (COVID-19).

Conditions

Interventions

TypeNameDescription
DRUGFingolimod 0.5 mgEach patient in the fingolimod treatment group was given 0.5 mg of fingolimod orally once daily, for three consecutive days

Timeline

Start date
2020-02-22
Primary completion
2020-07-01
Completion
2020-07-01
First posted
2020-02-21
Last updated
2020-11-13

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04280588. Inclusion in this directory is not an endorsement.