NCT04280367

Learning and Executive Function Disorders in Children and Psychosis Risk at Adult-age

Childhood Learning and Executive Function Disorders and Risk of Psychosis in the Adulthood

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 15 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of the study aims to study transition toward schizophrenia in patients with learning disorders, and to compare the risk between patients with specific learning disorders, and patients with complexed learning disorders (by two types: patients with other neuro-developmental disorders including executive function disorders, and patients with anxiety).

Detailed description

As secondary objectives, the study aims to: * argue the clinical predicted markers (neuropsychological) transition toward psychosis. * test the feasibility and the acceptability of a early diagnosis for a potential applicable guidance for different referent centers of learning in French territory. * have a better classification of patients with learning disorders in order to target a prospective primary prevention of risk of psychosis via the questionnaires (AQ of Baron-Cohen: Autism-spectrum quotient auto-questionnaire; Inventory of Beck Anxiety Inventory, auto-questionnaire for panic disorder and general anxiety; Liebowitz Social Anxiety Scale). * improve identification of the early signs and the early emerging psychological diseases intervention management (schizophrenia). * Psychic disability: prevent and reduce non-seeking care and accompaniment situations, and risk of rupture of care. * permitting better care of psychosocial rehabilitation with cognitive evaluation. This study will be conducted in Centre de référence des troubles du langage et des apprentissages, Hôpital Raymond Poincaré, APHP, in France.

Conditions

• Schizophrenia
• Learning Disorders
• Executive Function Disorders

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Standardised semi-structured talk	Comprehensive assessment of at-risk mental states (CAARMS) will be used.
DIAGNOSTIC_TEST	Autistic spectre disorder screening	Autism-spectrum quotient (AQ) auto-questionnaire will be used.
DIAGNOSTIC_TEST	Anxiety measuring	An inventory for measuring clinical anxiety: Beck Anxiety Inventory (BAI); Liebowitz Social Anxiety Scale.

Timeline

• Start date: 2020-01-28
• Primary completion: 2020-05-29
• Completion: 2020-05-29
• First posted: 2020-02-21
• Last updated: 2023-08-22

Locations

1 site across 1 country: France