Trials / Withdrawn
WithdrawnNCT04280237
Pharmacological Study of Cefazolin Antibioprophylaxis in Liver Transplantation
- Status
- Withdrawn
- Phase
- —
- Study type
- Observational
- Enrollment
- 0 (actual)
- Sponsor
- University Hospital, Tours · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study describes Cefazolin pharmacokinetics variation to target levels during liver transplantation.
Detailed description
Cefazolin is one of the many drugs used in antibiotic prophylaxis during liver transplantation. However there are no study describing its pharmacokinetics during liver transplantation. Due to the severe pharmacokinetics interactions caused by both prior hepatopathy and surgical techniques we suppose that Cefazolin blood levels are very different from those targeted for antibiotic prophylaxis. This study aim to describe pharmacokinetics of Cefazolin during liver transplantation in order to adapt antibiotic prophylaxis strategy in case of unadapted measured levels.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Blood samples | Blood samples |
Timeline
- Start date
- 2020-03-01
- Primary completion
- 2020-03-18
- Completion
- 2020-03-18
- First posted
- 2020-02-21
- Last updated
- 2021-04-29
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04280237. Inclusion in this directory is not an endorsement.