NCT04275557

Using Radiogenomics to Predict Malignant Potential of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Using Radiogenomics to Noninvasively Predict the Malignant Potential of Intraductal Papillary Mucinous Neoplasms (IPMNs) of the Pancreas and Uncover Hidden Biology

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,174 (estimated)
• Sponsor: H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The Florida Pancreas Collaborative wants to partner with individuals who are known to have, or are suspected to have a pancreatic lesion, tumor, cyst, mass, cancer, or pancreatitis and are undergoing diagnosis and treatment at a participating institution. The goals of this project are to build a large database of information obtained from blood, tissue, medical images, surveys and information from routine care to develop noninvasive diagnostic approaches that could be used as decision-making tools to effectively personalize clinical care.

Conditions

• Pancreatic Cancer
• Pancreatic Cyst

Interventions

Type	Name	Description
OTHER	Blood Sample collection	Participants will be asked to donate blood at baseline (+/- 30 days of diagnosis date), 4-6 weeks post-surgery, if applicable, and at the time of follow-up (approximately 1 year and approximately 2 years after baseline).
OTHER	Tissue sample collection	At the time of tissue biopsy and surgical resection (if applicable), pancreatic tumor tissue, muscle, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.
OTHER	Data collection	Participants will be asked to complete questionnaires at baseline and at 1 year and 2 year follow-ups.

Timeline

• Start date: 2020-02-18
• Primary completion: 2026-06-01
• Completion: 2027-06-01
• First posted: 2020-02-19
• Last updated: 2025-12-04

Locations

3 sites across 1 country: United States