NCT04274673

The Correlation Between Cotinine and Postoperative Acute and Chronic Pain After Hysterectomy

The Correlation Between the Cotinine Levels in Urine and Postoperative Acute and Chronic Pain in Open Abdominal Hysterectomy Patients

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 158 (estimated)
• Sponsor: Mustafa Kemal University · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

It is known that there is an association between smoking and acute/chronic pain. But it is so difficult to assess this relation with asking questions to the patients in the preoperative period. Because of that we want to measure the levels of the cotinine in the urine and later assess the correlation with acute and chronic pain in hysterectomy patients.

Detailed description

It is well-known that smoking is very common in the public. The chronic pain after hysterectomy is 20-40%. The open abdominal hysterectomy ratio is 75% of all hysterectomy operations in our country. We know that the reasons of postoperative acute and chronic pain is multifactorial. One of them is smoking which affects the postoperative pain. The best way of measuring the level of cotinine is assesing the urine of the patient. We collect the first urine after induction. In this study, we aimed to investigate the correlation between the levels of urine cotinine and the acute and chronic postoperative pain in hysterectomy patents.

Conditions

• Chronic Pain, Acute Pain, Cotinine, Hysterectomy

Interventions

Type	Name	Description
DEVICE	measuring cotinine level	Measuring of the cotinine levels

Timeline

• Start date: 2019-12-01
• Primary completion: 2020-05-13
• Completion: 2020-05-15
• First posted: 2020-02-18
• Last updated: 2020-02-18

Locations

1 site across 1 country: Turkey (Türkiye)