NCT04273906

End-range Mobilization on Pressure Pain Threshold

End-range Mobilization Effecting Pressure Pain Threshold in Knee Osteoarthritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of Pecs · Academic / Other
• Sex: Female
• Age: 60 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Pain in knee osteoarthritis (OA) represents increased pain intensity due to peripheral and central sensitivity. Pressure pain threshold (PPT) is a widely applied (used) method for measuring the magnitude of peripheral and central sensitivity in knee OA. Among several manual therapy techniques increasing PPT in knee OA, the effect of end-range mobilization has not been evaluated so far. The aim of this study was to investigate the immediate effect of end-range mobilization compared to placebo on increase of PPT and some function-related measures.

Detailed description

Knee osteoarthritis (OA) is the most common form of arthritis contributing to a major cause of disability worldwide. Although many mechanisms may contribute to knee pain severity, the patient-reported hyperalgesia can be attributed to peripheral and central sensitivity in knee OA. Pressure pain threshold (PPT) measurement is a simple and commonly applied method for measuring somatosensory function in musculoskeletal disorders, just as in knee OA. Many trials have shown a lower PPT value in knee OA underlining the presence of peripheral and central sensitivity compared to healthy controls. Manual therapy techniques, as a preferred treatment option, may not only alleviate pain, but also increase pain tolerance to locally applied mechanical pressure. Positive results of different manual therapy techniques on increase of PPT has been reported in knee OA. End-range manual therapy is an option for the decrease of sensitivity in knee OA; however, the effect of end-range mobilization has not been evaluated so far in knee OA.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	End-range mobilization	End-range mobilization performed in end-range of the tibiofemoral joints' flexion and extension
PROCEDURE	Placebo technique	Hands-on technique performed in end-range of the tibiofemoral joints' flexion and extension

Timeline

• Start date: 2020-02-12
• Primary completion: 2020-03-12
• Completion: 2020-03-12
• First posted: 2020-02-18
• Last updated: 2020-10-19

Locations

1 site across 1 country: Hungary