NCT04271683

Safe Use of CPAP and PEEP During Induction of General Anesthesia

Safe Use of CPAP During Preoxygenation and PEEP After Apnoea During Induction of General Anesthesia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Region Västmanland · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study compares the safety of using pressure controlled ventilation with a positive end-expiratory pressure (PEEP) during induction of general anaesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.

Detailed description

Using a continuous positive pressure (CPAP) during preoxygenation, followed by pressure controlled ventilation with PEEP after apnoea during induction of general anesthesia, might offer several benefits but safety issues needs more investigation. This study compares the safety of using pressure controlled with PEEP during induction of general anesthesia immediately after apnoea to a standard method starting ventilation manually without PEEP immediately after apnoea.

Conditions

• General Anesthesia

Interventions

Type	Name	Description
PROCEDURE	Pressure controlled ventilation with PEEP	The intervention consists of starting ventilation after apnoea during induction of general anesthesia with pressure controlled ventilation with PEEP instead of manually without PEEP.
PROCEDURE	Manual ventilation without PEEP	The intervention consists of starting ventilation after apnoea during induction of general anesthesia manually instead of with pressure controlled ventilation with PEEP.

Timeline

• Start date: 2021-10-19
• Primary completion: 2021-12-20
• Completion: 2021-12-21
• First posted: 2020-02-17
• Last updated: 2023-05-08

Locations

1 site across 1 country: Sweden