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UnknownNCT04270071

Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris

Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris: Randomised, Double Blind, Placebo Controlled Trial

Status
Unknown
Phase
Phase 4
Study type
Interventional
Enrollment
80 (estimated)
Sponsor
Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Academic / Other
Sex
All
Age
40 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study is a randomized, double-blind, placebo-controlled, parallel clinical trial in Chinese population with stable angina pectoris. The purpose is to determine the efficacy and safety of Yangxin Shengmai Granules in the treatment of stable angina pectoris.

Detailed description

Yangxin Shengmai granules is a Chinese patent medicine composed of ginseng, Ophiopogon japonicus, Salvia miltiorrhiza, Schisandra chinensis, etc. It is used for the treatment of chest pain caused by Qi-yin deficiency and blood stasis in traditional Chinese medicine. The symptoms include chest tightness, chest pain, palpitation, shortness of breath, fatigue, dry mouth and dry throat. Clinical applications suggested that Yangxin Shengmai granules were safe and effective in the treatment of coronary heart disease. However, high-quality clinical trials are still needed to further confirm, so as to provide theoretical basis for the treatment of stable angina pectoris with traditional Chinese medicine. The study is designed to determine the efficacy and safety of Yangxin Shengmai Granules in the treatment of stable angina pectoris.

Conditions

Interventions

TypeNameDescription
DRUGYangxin ShengmaiYangxin Shengmai Granules
DRUGYangxin Shengmai placeboYangxin Shengmai placebo have an identical appearance and scent as the active treatment granules.
DRUGnitroglycerin tabletsBe used when angina attack

Timeline

Start date
2020-12-01
Primary completion
2021-10-01
Completion
2021-12-01
First posted
2020-02-17
Last updated
2020-11-13

Source: ClinicalTrials.gov record NCT04270071. Inclusion in this directory is not an endorsement.