NCT04267510

Clinical and Molecular Aspects of Early Osteoarthritis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 65 (actual)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 7 Years
• Healthy volunteers: Not accepted

Summary

The etiology of osteoarthritis is varied, ranging from multifactorial, environmental to monogenic. In individuals in whom osteoarthritis appears earlier than in the general population, it is called early osteoarthritis. To our knowledge, there are no large-scale genetic studies on people with early osteoarthritis. The investigators therefore sought to study the causes of monogenic osteoarthritis in people suffering from early non-syndromic osteoarthritis. Material and method From 2013 to 2019, experts in constitutional bone disease sent patients with non-syndromic early osteoarthritis for genetic analysis to our center of competence for constitutional bone diseases. The sequencing of a panel of genes was carried out by NGS.

Conditions

• Early Osteoarthritis

Timeline

• Start date: 2013-01-01
• Primary completion: 2019-12-01
• Completion: 2020-01-01
• First posted: 2020-02-13
• Last updated: 2020-02-13

Locations

1 site across 1 country: France