NCT04265989

A New Classification and Interventional Therapy for Coronary Artery Ectasia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: China National Center for Cardiovascular Diseases · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is aim to present a new classification for coronary artery ectasia and find the best interventional therapy for different types of patients were treated and studied.

Detailed description

Coronary artery ectasia refers to a variety of reasons cause coronary artery expansion, its diameter is more than 1.5 times that of the adjacent normal coronary artery. Clinical symptoms include angina, myocardial infarction and sudden death.At present, there is no consensus on the mechanism and treatment of the disease, which may be related to the structural failure of the vessel wall and abnormal hemodynamics in the dilated segment.Most of the existing studies are case reports or single-center retrospective analysis of small samples, with low level of evidence.As a common fluid analysis method in the field of engineering, computational fluid dynamics can effectively simulate the movement and stress state of blood under reasonable model assumptions.By comparing the preoperative and postoperative data of real cases, the validity of simulation analysis results can be tested.The purpose of this study is to carry out a multi-center study combining morphological and hemodynamic factors, to propose a new classification and interventional treatment strategy for atherosclerotic coronary artery ectasia, and to provide evidence-based medical evidence for the development of treatment guidelines.

Conditions

• Coronary Artery Ectasia

Interventions

Type	Name	Description
DEVICE	Single BMS	Single bare metal stent covered the coronary artery aneurysm
DEVICE	Single or Double BMS	Single or double layer bare metal stents covered the coronary artery aneurysm
DEVICE	Single or Double BMS	Treated with single or double layer bare metal stents
DEVICE	BMS+DES	Treated with bare metal stent combined with drug eluting stent

Timeline

• Start date: 2019-11-01
• Primary completion: 2021-11-30
• Completion: 2021-11-30
• First posted: 2020-02-12
• Last updated: 2020-02-17

Locations

1 site across 1 country: China