NCT04263246

Medium-Term Supplementation With Herbal Extract for Exercise Performance and Antioxidant Status

Does Medium-Term Supplementation With PhytoDyNAmic Affect Exercise Performance and Antioxidant Status in Healthy Men and Women: A Randomized Controlled Trial?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: University of Novi Sad, Faculty of Sport and Physical Education · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Accepted

Summary

We evaluated here the effects of 6-week intervention with herbal supplement on exercise performance outcomes and serum biomarkers of antioxidant status. In addition, we also assessed the long-term effects (6-month) of the intervention in elderly adults.

Detailed description

Experimental protocol * Double-blind, randomized, placebo-controlled cross-over trial * 6-week intervention trial (with additiional follow-up arm after 6 months) * Experimental intervention (PhytoDyNAmic) = 6 capsules per day * Placebo (inulin) = 1 g per day b.i.d. * Administration = 3 capsules with breakfast and 3 capsules with dinner * Wash-out period = 2 weeks * No changes in physical activity patterns and diet during the study Outcomes assessed at baseline and at each follow-up: * Exercise performance during incremental running-to-exhaustion test * Serum biomarkers of antioxidant status * Total antioxidant capacity (TAC) * Superoxide dismutase (SOD) * Telomerase activity Early termination criteria \- Serious subjective side effects of an intervention (e.g. nausea, vomiting, bloating)

Conditions

• Exercise Performance

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	PhytoDyNAmic	PhytoDyNAmic (6 capsules per day)
DIETARY_SUPPLEMENT	Inulin	Inulin (6 capsules per day)

Timeline

• Start date: 2020-09-15
• Primary completion: 2020-12-01
• Completion: 2020-12-01
• First posted: 2020-02-10
• Last updated: 2022-03-25

Locations

1 site across 1 country: Serbia