NCT04262609

Faecal Incontinence in Prostate Cancer Survivors Treated Whith Radiotherapy

Faecal Incontinence in Prostate Cancer Survivors Treated With Moderately Hypofractionated Radiotherapy

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Consorci Sanitari de Terrassa · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: —

Summary

The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with the degree of faecal incontinence.

Detailed description

The investigators know that high doses of irradiation in the anal sphincter are associated with more chronic fecal leaks in survivors irradiated by normofractionated radiotherapy prostate cancer. The safe dose of irradiation of the anal sphincter with radiotherapy modern techniques (volumetric modulated arc therapy with moderately hypofracctionation) is unknown. Urgency and faecal incontinence greatly affects the quality of life of these patients. Therefore, it is interesting to implement strategies to protect the anatomical structures involved in fecal continence. The objective of the study is to determine the incidence of faecal incontinence in prostate cancer survivors treated with modern moderately hypofractionated radiation therapy and correlate the dose received by the anal sphincter with the degree of faecal incontinence. The investigators also want to evaluate the quality of life of these patients

Conditions

• Faecal Incontinence
• Prostate Cancer

Interventions

Type	Name	Description
RADIATION	hypofractionated radiotherapy	volumetric modulated moderately fractionated arc therapy

Timeline

• Start date: 2019-07-01
• Primary completion: 2026-02-01
• Completion: 2026-12-01
• First posted: 2020-02-10
• Last updated: 2026-03-19

Locations

1 site across 1 country: Spain