NCT04260139

Lymph Node Yield in Colon Cancer Resection Specimens

Macroscopic Evaluation of Colon Cancer Resection Specimens to Predict Metastatic Lymph Node Yield

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Bagcilar Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this study, we aimed to develop a predictive model of lymph node yield in a series of colon cancer resection specimens with detailed anatomic and surgical technique data.

Detailed description

Lymph node yield in colon resection specimens has been associated with the accuracy of staging and cancer outcomes. It has been proposed that the more central the mesenteric vascular ligation, the greater the nodal yield. However, the optimal number of harvested nodes is still a matter of debate. We prospectively evaluated the relation between specimen properties such as lenght, area, tumor location and pedicle length to the number of harvested nodes and rate of node positivity.

Conditions

• Colon Cancer
• Lymph Node Metastases

Interventions

Type	Name	Description
PROCEDURE	Calculation of metric variables on the colectomy specimens.	Calculation of metric variables on the colectomy specimens including Lengths as mm 1. Proximal colon, 2. Ileum in cases with right hemicolectomy only, 3. Proximal border, 4. Tumor, 5. Distal border, 6. Total specimen, 7. Vascular pedicle, the longitudinal distance between the nearest bowel wall and the end of ligated major vascular pedicle depending on the tumor's localization, 2. Colonic mesenteric area as mm2.

Timeline

• Start date: 2019-09-01
• Primary completion: 2020-07-01
• Completion: 2020-10-01
• First posted: 2020-02-07
• Last updated: 2020-11-13

Locations

1 site across 1 country: Turkey (Türkiye)