NCT04255173

Anthropometric And Body Composition Measurements Related To Osteoporosis In Geriatric Population

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 571 (actual)
• Sponsor: Istanbul Medeniyet University · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

The patients who consulted to the geriatric outpatient clinic between 2018 and 2019 were included in the study. The inclusion criterions were being at or over the age of 65 and diagnosed with osteoporosis according to WHO criteria. Exclusion criteria include vertebral fracture due to known accidental traumas, history of drug therapy in the past year (biphosphonate, estrogen replacement therapy, glucocorticoids ), history of co-morbidities as malignancy, radiotherapy or chemotherapy, renal failure, hyperthyroidism, primer hyperparathyroidism, rheumatic disease or adrenal diseases. Initially, a demographic form including age, sex, comorbidities, weight, height was filled by the participants. Body mass index (BMI, ratio of height and weight, expressed as kg/m2) calculated. Patients waist and hip circumference was measured (cm). Fat percentage and skeletal muscle mass (SMM) was calculated by using bioimpedance analysis (BIA) (Tanita TBF 300; Tanita Corp., Tokyo, Japan). Skeletal muscle index (SMI) was calculated from BIA-based skeletal muscle mass with a formula as SMM/height \[m2\] \[8\]. ABSI is measured as waist circumference (m) / (BMI(kg)2/3x Height(m)5/6) \[4\]. Osteoporosis was evaluated by using dual energy x-ray absorptiometry (DXA). According to the T-scores calculated from femur neck (FN) and lumbar spine (LS), subjects divided into 3 groups as following: a) normal: T-score is greater than -1 SD, b) osteopenia: T-score is between -1 and -2.5 SD, c) osteoporosis: T-score is lower than -2.5 SD. Physical activity levels of patients were evaluated with The Rapid Assessment of Physical Activity (RAPA) aerobic assessment \[9\]. Patients divided into 5 groups as following: 1 = sedentary, 2 = underactive, 3 = regular underactive (light activities), 4 = regular underactive, and 5 = regular active). The study protocol was approved by the ethics committee (2018/0478) and all participants gave written informed consent.

Conditions

• Osteoporosis Senile
• Obesity, Visceral

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Body mass index	Body mass index is calculated as a ratio of height and weight, expressed as kg/m2
DIAGNOSTIC_TEST	waist circumference	waist circumference is measured as cm
DIAGNOSTIC_TEST	hip circumference	hip circumference is measured as cm
DIAGNOSTIC_TEST	height	height is measured as cm
DIAGNOSTIC_TEST	Fat percentage	Fat percentage and skeletal muscle mass (SMM) was calculated by using bioimpedance analysis (BIA) (Tanita TBF 300; Tanita Corp., Tokyo, Japan).
DIAGNOSTIC_TEST	Skeletal muscle index	Skeletal muscle index (SMI) was calculated from BIA-based skeletal muscle mass with a formula as SMM/height \[m2\].
DIAGNOSTIC_TEST	A body shape index (ABSI)	ABSI is measured as waist circumference (m) / (BMI(kg)2/3x Height(m)5/6)
DIAGNOSTIC_TEST	Dual energy x ray absorptiometry (DXA)	Osteoporosis is diagnosed with DXA scores. According to the T-scores calculated from femur neck (FN) and lumbar spine (LS), subjects divided into 3 groups as following: a) normal: T-score is greater than -1 SD (standard deviation), b) osteopenia: T-score is between -1 and -2.5 SD, c) osteoporosis: T-score is lower than -2.5 SD.
DIAGNOSTIC_TEST	The Rapid Assessment of Physical Activity (RAPA) aerobic assessment	Physical activity levels of patients were evaluated with The Rapid Assessment of Physical Activity (RAPA) aerobic assessment. Patients divided into 5 groups as following: 1 = sedentary, 2 = underactive, 3 = regular underactive (light activities), 4 = regular underactive, and 5 = regular active).

Timeline

• Start date: 2018-01-01
• Primary completion: 2019-11-01
• Completion: 2019-12-01
• First posted: 2020-02-05
• Last updated: 2020-02-05

Locations

1 site across 1 country: Turkey (Türkiye)