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UnknownNCT04255017

A Prospective/Retrospective,Randomized Controlled Clinical Study of Antiviral Therapy in the 2019-nCoV Pneumonia

An Open, Prospective/Retrospective, Randomized Controlled Cohort Study to Compare the Efficacy of Three Antiviral Drugs(Abidol Hydrochloride, Oseltamivir and Lopinavir/Ritonavir) in the Treatment of 2019-nCoV Pneumonia.

Status
Unknown
Phase
Phase 4
Study type
Interventional
Enrollment
400 (estimated)
Sponsor
Tongji Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

At present, there is no specific and effective antiviral therapy.In this study, an open, prospective/retrospective, randomized controlled cohort study was designed to compare the efficacy of three antiviral drugs in the treatment of 2019-nCoV pneumonia by studying the efficacy of abidol hydrochloride, oseltamivir and lopinavir/ritonavir in the treatment of 2019-nCoV viral pneumonia, and to explore effective antiviral drugs for new coronavirus. To provide reliable evidence-based medicine basis for the treatment of viral pneumonia caused by new coronavirus infection.

Conditions

Interventions

TypeNameDescription
DRUGAbidol hydrochlorideAbidol hydrochloride (0.2g once, 3 times a day,2 weeks)was added on the basis of group I.
DRUGOseltamivirOseltamivir(75mg once, twice a day,2 weeks) was added on the basis of group I.
DRUGLopinavir/ritonavirLopinavir/ritonavir (500mg once, twice a day,2 weeks)was added on the basis of group I.

Timeline

Start date
2020-02-01
Primary completion
2020-06-01
Completion
2020-07-01
First posted
2020-02-05
Last updated
2020-03-17

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04255017. Inclusion in this directory is not an endorsement.