NCT04253730

Characterization of Corticospinal Excitability During Progressive Skin Cooling

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: University of Manitoba · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study characterizes the changes in corticospinal excitability that accompany basic cold stress via skin cooling that result in reduced skin or core temperature and shivering.

Detailed description

Cold stress is known to impair both fine and gross motor movement. Reductions in performance may have life threatening consequences in survival situations where maintenance of muscle control is necessary. Much of the effects cooling has on muscle performance is directly due to its effects on muscle tissue itself, whereas less is known about the effects on the central nervous system. Therefore, the purpose of the study was to characterize corticospinal excitability that accompanies basic cold stress via progressive skin cooling, resulting in reductions in skin (Tsk) or core (Tco) temperature and shivering.

Conditions

• Hypothermia Due to Cold Environment

Interventions

Type	Name	Description
OTHER	Cold Stress	60-90 mins of cooling via a liquid perfused suit circulating \~4-10°C liquid.

Timeline

• Start date: 2019-08-22
• Primary completion: 2022-03-01
• Completion: 2022-06-01
• First posted: 2020-02-05
• Last updated: 2022-12-06

Locations

1 site across 1 country: Canada