NCT04253275

Identification of Biomarkers in Ischemic Stroke - Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: University Hospital, Brest · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

The objective of the study is to determine RNA blood biomarker based on 9 genes already identified in experimental studies, whose expression would be significantly increased in patient with ischemic stroke compared to controls.

Detailed description

This is a monocentric study. It's a case-control study with case being first-ever ischemic stroke and controls being healthy (stroke free) subject patients paired for age, sex and cardiovascular risk or hemorrhagic stroke paired for age and sex. Patients are followed for one year. Blood samples will be taken at inclusion, 12h, 24h, 48h, 7d, 3m and 1y. Microvesicles samples will be taken at inclusion, 7d and 3M.

Conditions

• Stroke, Ischemic
• Stroke Hemorrhagic

Interventions

Type	Name	Description
GENETIC	blood samples	Blood samples will be taken at inclusion, 12h, 24h, 48h, 7d, 3m and 1y for patients ; at inclusion, 3m and 1y for controls. Microvesicles samples will be taken at inclusion, 7d and 3M ; at inclusion and 3M for controls.
DIAGNOSTIC_TEST	MRI without injection	MRI at inclusion for controls

Timeline

• Start date: 2020-11-24
• Primary completion: 2024-02-06
• Completion: 2024-02-06
• First posted: 2020-02-05
• Last updated: 2024-03-04

Locations

1 site across 1 country: France