NCT04252781

Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 35 Years
• Healthy volunteers: Not accepted

Summary

Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs. The impact on the health system of undiagnosed patients, up to 70% of patients, is increasingly documented. However, systematic spirometry screening remains controversial among smokers in the absence of data to link the detection of new patients with improved management and clinical events and health goals. More generally, there is little data on the evolution of patients in real life once they have entered the care system. The premise is that with systematic screening in general medicine, it is possible to identify the evolution of newly diagnosed COPD patients, to distinguish the different possible evolutions according to the initial phenotype and the management.

Detailed description

A description of the population from which the groups or cohorts will be selected Smokers who have a screening spirometry for COPD, either in general medicine, at a pulmonologist or in the CHIC or Henri Mondor hospital respiratory function tests department. After screening, an equal number of men and women COPD will be included (150 men and 150 women). 1500 smokers will be included to reach 300 smokers with COPD.

Conditions

• Smokers
• Chronic Obstructive Pulmonary Disease

Interventions

Type	Name	Description
OTHER	Exhaustive exploration	* clinical investigations * imagery * blood assessment * functional respiratory investigations * muscle function / skeletal muscle index

Timeline

• Start date: 2020-08-20
• Primary completion: 2025-01-07
• Completion: 2026-02-20
• First posted: 2020-02-05
• Last updated: 2025-01-09

Locations

1 site across 1 country: France