NCT04252469

Efficacy of Pre-intubation Chlorhexidine Oral Care on Health Outcomes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 210 (actual)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This single-centre, single-blind, randomised controlled study with parallel-group design was conducted in Yun Ling, Taiwan between May 2019 and August 2019. Participants were randomly allocated to an intervention (mouth care using 0.12% CHX before intubation) or control (standard care) group on a 1:1 basis. This study was approved by the institutional review board of National Taiwan University Hospital, Taiwan (IRB No.201806086RINB). Each participant completed written informed consent after explanation of this study and advised that they could withdraw anytime.

Detailed description

Participants were recruited at the operation room of a teaching hospital. Participants were included if they met the following criteria: 18-80 years of age, American Society of Anesthesiologists, ASA) class 1-3, scheduled for surgery under endotracheal tube intubation general anesthesia. Patients were excluded if they were diagnosed with upper or lower respiratory tract disease, including COPD, cold, had oral ulcer, scheduled to have a respiratory-related surgical procedure, had endotracheal tube intubated.

Conditions

• Intratracheal Intubation
• Surgery
• Anesthesia

Interventions

Type	Name	Description
OTHER	Oral care	oral care using 20mL of 0.12% CHX and gargling with 30 seconds.

Timeline

• Start date: 2019-05-01
• Primary completion: 2019-08-31
• Completion: 2019-08-31
• First posted: 2020-02-05
• Last updated: 2020-02-05

Locations

1 site across 1 country: Taiwan