Trials / Completed
CompletedNCT04252027
Therapeutic Drug Monitoring of Fluconazole in Critically Ill Patients
Therapeutic Drug Monitoring of Fluconazole in Critically Ill Patients: a Longitudinal Follow-up of Trough Levels
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 43 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This prospective study will research the exposure and its variability to fluconazole after longitudinal administration in critically ill patients
Detailed description
An open label, monocenter pharmacokinetic study will be carried out in critically ill patients, admitted at the University Hospitals Leuven, receiving multiple dose treatment with fluconazole. The exposure to fluconazole in the ICU cohort over multiple days of treatment will be documented. Moreover, variability and the correlating covariates that can influence the fluconazole concentration, will be determined.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Sample collection | Plasma and urine sample collection |
Timeline
- Start date
- 2019-04-23
- Primary completion
- 2020-03-05
- Completion
- 2020-03-05
- First posted
- 2020-02-05
- Last updated
- 2021-04-28
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT04252027. Inclusion in this directory is not an endorsement.