NCT04249297

Predictors of Pregnancy Rate in Assisted Reproductive Technology According to Actual Guidelines

Multicenter Open-Label Observational Program to Research on Predictors of Pregnancy Rate in Assisted Reproductive Technology in the Russian Population and Kazakhstan Population According to Actual International and National Guidelines (IRIS)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,150 (estimated)
• Sponsor: Abbott · Industry
• Sex: Female
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Goals: To explore the association of probability of pregnancy with certain prognostic factors in patients undergoing assisted reproductive technology in Russian population according to international and national guidelines.

Detailed description

Research on significant factors (predictors) of pregnancy rate in In Vitro Fertilization (IVF) and Intracytoplasmatic Sperm Injection (ICSI) cycles in Russian population according to actual national and international guidelines in patients using oral dydrogesterone for luteal phase support in assisted reproductive technology. Investigating the strength of the relationship and assessing coefficients of impact on the pregnancy rate. Creating a predictive table of Clinical Pregnancy in IVF and ICSI cycles and 4-5 most impact predictors.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	Duphaston® (Dydrogesteron)	No intervention. Description of routine practice only. Prescribed Duphaston® according local marketing authorization and international and Russian In-Vitro Fertilization guidelines for luteal phase support as part of an Assisted Reproductive Technology (1 tablet 3 times a day starting at the day of oocyte retrieval).

Timeline

• Start date: 2020-03-03
• Primary completion: 2022-03-01
• Completion: 2022-12-01
• First posted: 2020-01-30
• Last updated: 2021-12-28

Locations

52 sites across 2 countries: Kazakhstan, Russia