NCT04247373

The MEC90 of Epidural Ropivacaine Blunting Hemodynamic Changes to Pneumoperitoneum

The MEC90 of Epidural Ropivacaine Blunting Hemodynamic Changes to Pneumoperitoneum in the Patients Undergoing Laparoscopic Gastrectomy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Keimyung University Dongsan Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Investigators want to find the concentration of epidural ropivacaine, which can block hemodynamic changes in the onset of pneumoperitoneum in the laparoscopic gastrectomy.

Detailed description

According to previous patient's response, the investigators will allocate the concentration of ropivacaine of next patient during Co2 insufflation. And, for this allocation of concentration of ropivacaine, the investigators use biased coin design up-and-down method. Based on the practices, the starting concentration is 0.375 %, and the step size of concentration is 0.125%.

Conditions

• Laparoscopic Gastrectomy

Interventions

Type	Name	Description
DRUG	Ropivacaine	According to previous patient's response, the investigators will allocate the concentration of ropivacaine of next patient during Co2 insufflation. And, for this allocation of concentration of ropivacaine the investigators use biased coin design up-and-down method.

Timeline

• Start date: 2020-01-01
• Primary completion: 2020-08-01
• Completion: 2020-08-01
• First posted: 2020-01-30
• Last updated: 2020-01-30