Trials / Recruiting
RecruitingNCT04246944
Induced Membrane Properties in Children and Adults
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Centre Hospitalier Universitaire, Amiens · Academic / Other
- Sex
- All
- Age
- 9 Months – 60 Years
- Healthy volunteers
- Not accepted
Summary
Bone reconstruction in critical sized defect (CSD) remains a real challenge in orthopedic surgery in children and adults. The Masquelet technique is an innovative therapeutic technique, which offers a bone reconstruction in two steps, by the formation of an induced membrane (IM) around a polymethylmethacrylate (PMMA) spacer placed into the bone defect. After, PMMA removal, the cavity is filled with corticocancellous graft allowing bone healing. Up to date, all angiogenesis and osteogenic properties of IM remain unknown. The purpose of this study is to characterize angiogenesis and osteogenic properties of IM in children and adults.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | harvesting induced membrane | The induced membrane will be harvested during the second step of the bone reconstruction. |
Timeline
- Start date
- 2019-05-23
- Primary completion
- 2030-01-01
- Completion
- 2030-01-01
- First posted
- 2020-01-29
- Last updated
- 2025-06-08
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT04246944. Inclusion in this directory is not an endorsement.