NCT04244747

Labor Induction After Cesarean Section: Outcome, Hormonal Trends

The Hormonal Milieu With Different Methods of Labour Induction: a Prospective Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Western Galilee Hospital-Nahariya · Other Government
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Objectives- To compare changes in labour-associated maternal and fetal hormone levels during breast stimulation, balloon induction and spontaneous labour. To compare efficacy and safety of labour induction methods in women with previous caesarean section. Design- Participants were randomized to undergo induction of labour by breast stimulation or intracervical balloon compared to spontaneous labour (controls). Setting- A single tertiary hospital Population- women at term, with previous caesarean section

Detailed description

Maternal serum levels of oxytocin, prostaglandin F2α, prostaglandin E2, prolactin, estradiol and cortisol levels were analyzed at 0, 3 and 6 hours post induction initiation, including the two groups catheter balloon and breast stimulation and controls in spontaneous labor. Fetal umbilical cord hormones were measured in the three mentioned above groups. Clinical outcomes were documented in the two induction groups.

Conditions

• Induction of Labor
• Previous Cesarean Section
• Hormonal Changes

Interventions

Type	Name	Description
DEVICE	induction of labor by breast stimulation
DEVICE	induction of labor by catheter balloon

Timeline

• Start date: 2016-01-01
• Primary completion: 2018-07-01
• Completion: 2020-01-01
• First posted: 2020-01-28
• Last updated: 2021-04-13

Locations

1 site across 1 country: Israel