Trials / Unknown
UnknownNCT04244383
Expression of Inflammasomes in HCV Patients
Expression of Inflammasomes in HCV Patients Before and After Treatment
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Assiut University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Hepatitis C virus has been identified a quarter of a decade ago as a leading cause of chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a minority of patients can clear the virus spontaneously during acute infection. Elimination of HCV during acute infection correlates with a rapid induction of innate and a delayed induction of adaptive immune responses. The majority of patients is unable to clear the virus and develops viral persistence despite the ongoing innate and adaptive immune response. The virus usually develops several strategies to escape these immune responses.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | interleukin IL-1beta and interleukin IL-18 | pro-inflammatory cytokines measured in the serum |
Timeline
- Start date
- 2020-01-01
- Primary completion
- 2020-06-01
- Completion
- 2020-07-01
- First posted
- 2020-01-28
- Last updated
- 2020-01-28
Source: ClinicalTrials.gov record NCT04244383. Inclusion in this directory is not an endorsement.