Trials / Completed
CompletedNCT04244149
Effect of an Exercise Bout in Plasma and Fecal Profile
Exploring the Effect of Exhaustive Exercise From a Metabolomic and Metagenomic Approach
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Universidad Europea de Madrid · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The aim of this project is to study the effect of a bout of exercise on the metabolomic profile of plasma and feces as well as its influence on the intestinal microbiota.
Detailed description
The practice of physical exercise has numerous health benefits, preventing the appearance and development of cardiovascular diseases and various types of cancer. Exercise causes changes in the vascular, muscular and pulmonary systems, etc. One of the benefits that can result from exercise modification of the intestinal microbiota and its metabolic profile. In order to identify the potential changes that exercise has on the intestinal microbiota and its metabolic profile, the purpose of this study is to identify changes in the plasma and fecal metabolome and in fecal microbiota associated with a bout of exercise
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Prolonged Exercise session | After a standardized warm-up of 10 minutes of continuous running on a treadmill at 60% of their maximum heart rate (HRmax), subjects will perform a maximum oxygen consumption test (VO2max) with a gas analyzer (UltimaTM Series, MGC Diagnostic Corporation, St. Paul, MN, USA. The protocol will start with a slope of 1% at a speed of 10 km/h, with increments of 0.3 km/h every 30 s until volitional exhaustion. Finally, ten minutes after the treadmill test, volunteers will run 1 kilometer (t1km) as fast as possible and the time needed to cover the distance will be recorded. |
Timeline
- Start date
- 2020-02-20
- Primary completion
- 2020-03-10
- Completion
- 2020-03-13
- First posted
- 2020-01-28
- Last updated
- 2020-06-22
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04244149. Inclusion in this directory is not an endorsement.