Clinical Trials Directory

Trials / Terminated

TerminatedNCT04242173

Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCC

A Single Arm Phase II Study of Cemiplimab-rwlc in Immunocompromised Patients With Unresectable Locally Recurrent and/or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
3 (actual)
Sponsor
H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this research study is to determine how people with weakened immune systems and unresectable (cannot be removed by surgery) locally recurrent and/or metastatic cutaneous squamous cell carcinoma (CSCC) respond to study treatment with Cemiplimab. Cemiplimab is approved for sale in United States by the U.S. Food and Drug Administration (FDA).

Conditions

Interventions

TypeNameDescription
DRUGCemiplimab-RwlcCemiplimab-rwlc will be administered as a flat dose of 350 mg IV over approximately 30 minutes every 21 days (+/- 3 days)

Timeline

Start date
2020-06-25
Primary completion
2022-05-26
Completion
2022-05-26
First posted
2020-01-27
Last updated
2022-11-04
Results posted
2022-07-14

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04242173. Inclusion in this directory is not an endorsement.