NCT04239378

Comparison of Autogenous Dentin Matrix Versus Bovine-Derived Xenograft for Socket Preservation

Clinical, Radiographic and Histomorphometric Comparison of Autogenous Demineralized Dentin Matrix Versus Bovine-Derived Xenograft for Socket Preservation: A Randomised Controlled Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Krishnadevaraya College of Dental Sciences & Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The present study is a human, prospective, randomised controlled clinical trial will be conducted to explore and compare the clinical, radiographic and histomorphometric outcome of autogenous demineralised dentin(DDM) versus bovine derived xenograft(DBM) for socket preservation procedure.

Detailed description

* After local anesthesia a full thickness flap will be minimally reflected buccally and lingually around the tooth not exceeding 3mm apical to the alveolar crest. * Tooth extraction will be performed using atraumatic extraction methods using Periotome. * After extraction, the socket will be thoroughly curetted, inspected and irrigated with sterile saline solution. * The socket satisfying the inclusion and exclusion criteria will be randomly allocated to either test or control group. * Intra surgical measurements will be recorded. * Socket preservation will be performed with either Demineralized dentin matrix DDM(TEST) or bovine derived xenograft DBM (CONTROL). Bone graft will be extended to the height of intra proximal bone. * Collagen membrane will be placed over the grafted site extending approximately 3mm apical to buccal and lingual crest. * Flaps will be approximated with sutures.

Conditions

• Alveolar Bone Resorption

Interventions

Type	Name	Description
PROCEDURE	socket preservation	Autogenous dentin matrix and collagen membrane(test group) Bovine derived xenograft and collagen membrane (control group)

Timeline

• Start date: 2019-12-10
• Primary completion: 2021-11-01
• Completion: 2021-11-01
• First posted: 2020-01-27
• Last updated: 2020-02-05

Locations

1 site across 1 country: India