Clinical Trials Directory

Trials / Completed

CompletedNCT04238715

A Study of E7090 in Participants With Unresectable Advanced or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor (FGFR) 2 Gene Fusion

A Multicenter, Open-Label, Phase 2 Trial of E7090 in Subjects With Unresectable Advanced or Metastatic Cholangiocarcinoma With FGFR 2 Gene Fusion

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
63 (actual)
Sponsor
Eisai Co., Ltd. · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The primary purpose of the study is to assess the objective response rate (ORR) of E7090 by Response Evaluation Criteria In Solid Tumors (RECIST) 1.1 based on independent imaging review (IIR) in participants with unresectable cholangiocarcinoma with FGFR2 gene fusion who failed gemcitabine-based combination chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGE7090E7090 tablets orally.

Timeline

Start date
2020-01-22
Primary completion
2025-11-03
Completion
2025-11-03
First posted
2020-01-23
Last updated
2026-03-02

Locations

56 sites across 2 countries: China, Japan

Source: ClinicalTrials.gov record NCT04238715. Inclusion in this directory is not an endorsement.