NCT04236115

Comparison of Articaine and Prilocaine for Extraction of Maxillary Teeth

Does Articaine, Rather Than Prilocaine, Increase the Success Rate of Anaesthesia for Extraction of Maxillary Teeth

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 95 (actual)
• Sponsor: Taibah University · Academic / Other
• Sex: All
• Age: 16 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Ninety-five patients, aged between 16 and 70 years old, were included in this study. Patients were divided into two groups. Group one received Articaine 4% with 1:00.000 Adrenalines. Group two received Prilocaine with 3% Felypressin (0.03 I.U. per ml). Onset time of anaesthesia was objectively evaluated by using electronic pulp testing.

Detailed description

85 patients in this study had successful local anaesthetic followed by extraction within the study duration time (10 minutes). However, there were six patients with failure anaesthesia (5 in prilocaine group and 1 in articaine group). By application Person's Chi-square test (x2), there were no significant differences in the number of the episodes of the anaesthetic success between articaine and prilocaine groups at time intervals (P-value = 0.5). T- test showed there have been no important variations within the mean onset time of anaesthesia for articaine and prilocaine buccal infiltrations (P-value =0.1).

Conditions

• Overcoming the Failure of Anaesthesia
• Maxillary Teeth
• Dental Extraction

Interventions

Type	Name	Description
DRUG	Articaine 4%	Articaine 4% is dental local anaesthetic agent
DRUG	Prilocain 3%	prilocaine is dental local anaesthetic agent
DRUG	Adrenalin	adrenaline is a vasoconstrictor
DRUG	Felypressin	Felypressin is a vasoconstrictor

Timeline

• Start date: 2017-09-20
• Primary completion: 2018-04-20
• Completion: 2018-06-20
• First posted: 2020-01-22
• Last updated: 2020-01-22

Locations

1 site across 1 country: Saudi Arabia