NCT04234724

Physiological Effects of ANGPTL3 Variants in Humans

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

To evaluate the role of ANGPTL3, on lipid metabolism. To explore the role of this protein on glucose metabolism.

Detailed description

Oral fast tolerance test, lipoprotein kinetics and a glucose tolerance test to evaluate the role of ANGPTL3, on lipid metabolism and to explore the role of this protein on glucose metabolism.

Conditions

• Hypocholesterolemia

Interventions

Type	Name	Description
OTHER	Kinetics test, oral fat tolerance test, and an oral glucose tolerance test.	Subjects will participate in a kinetics test, oral fat tolerance test, and an oral glucose tolerance test.

Timeline

• Start date: 2020-12-01
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2020-01-21
• Last updated: 2025-09-10

Locations

1 site across 1 country: United States