NCT04233320

Efficacy and Safety of Silicone Cream Containing Allium Cepa Extract

Efficacy and Safety of Silicone Cream Containing Allium Cepa Extract in Post-cesarean Surgical Scars Treatment

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (estimated)
• Sponsor: Chulalongkorn University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The objectives of this study were to evaluate efficacy and safety of silicone cream containing Allium Cepa extract in post-cesarean surgical scars treatment. Post-cesarean surgical scars were equally seperated into 2 parts (left part and right part). Silicone cream containing Allium Cepa extract or commercial scar gel was ramdomly assigned to apply on left part or right part of the scar. They will be applied 2 times per day (morning and evening) for 3 months. Patient and Observer Scar Assessment Scale (POSAS) , Vancouver scar scale (VSS), melanin index, and erythema index (using cutometer) were used for scar evaluation at 0, 1,2,and 3 months. Moreover, adverse effects were also observed.

Conditions

• Cicatrix

Interventions

Type	Name	Description
DEVICE	silicone cream containing Allium Cepa extract	silicone cream containing Allium Cepa extract contains 10% of Allium cepa bulb extract.
DEVICE	Commercial scar gel	Commercial scar gel is a topical silicone gel. It contains cyclic and polymeric siloxanes and Vitamin C ester.

Timeline

• Start date: 2020-02-01
• Primary completion: 2020-06-30
• Completion: 2020-09-30
• First posted: 2020-01-18
• Last updated: 2020-01-21