Trials / Completed
CompletedNCT04232033
The Physiological Effects of FGF21 on Alcohol Preference and Glucose Metabolism
The Physiological Effects of FGF21 on Alcohol Preference and Glucose Metabolism in Healthy Men
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- University Hospital, Gentofte, Copenhagen · Academic / Other
- Sex
- Male
- Age
- 20 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The primary objective is to evaluate taste preferences for alcohol during an intravenous infusion of the naturally occurring hormone fibroblast growth factor-21 (FGF21) and placebo (i.e. saline), respectively, in 20 healthy subjects. Secondary endpoints are to evaluate the effects of exogenous FGF21 (compared to placebo) on resting energy expenditure, preference for salt, sour and bitter taste qualities, sensations of hunger, thirst, appetite, satiety, headache and nausea, and makers of glucose metabolism (e.g. plasma/serum concentrations of glucose, C-peptide, insulin and glucagon).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Fibroblast growth factor 21 infusion | Infusion of Fibroblast growth factor 21 |
| OTHER | Placebo infusion (saline) | Infusion of Saline |
Timeline
- Start date
- 2021-05-01
- Primary completion
- 2022-06-14
- Completion
- 2024-12-01
- First posted
- 2020-01-18
- Last updated
- 2024-12-09
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT04232033. Inclusion in this directory is not an endorsement.