NCT04231006

Salvage HDR for Locally Recurrent Prostate Cancer

Salvage High Dose Rate Brachytherapy for Local Recurrence in Prostate Cancer: A Phase II Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Aarhus University Hospital · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study offers focal salvage brachytherapy for prostate cancer patients with a local recurrence after primary defintive radiotherapy

Detailed description

The aim of this study is to examine the efficacy and toxicity of focal salvage high dose rate brachytherapy (HDR BT) for patients with locally recurrent prostate cancer after definitive external beam radiotherapy. Furthermore, the investigators want to assess, whether it is feasible to perform salvage HDR BT as a focal treatment based on multiparametric (mp) pelvine MRI and PSMA PET/CT.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
RADIATION	High dose rate brachytherapy	High dose rate brachytherapy will be delivered to the site of recurrence within the prostate gland based on MRI and PSMA PET/CT

Timeline

• Start date: 2021-04-01
• Primary completion: 2025-03-01
• Completion: 2035-03-01
• First posted: 2020-01-18
• Last updated: 2021-07-21

Locations

1 site across 1 country: Denmark