NCT04230772

Clinical Outcomes of NOSES Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer

A Randomized Controlled Trial Comparing Clinical Outcomes of Natural Orifice Specimen Extraction Surgery Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 550 (estimated)
• Sponsor: Taiyuan Li · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In this study, the investigators will compare the clinical outcomes of the natural orifice specimen extraction surgery versus traditional robotic-assisted surgery in the treatment of colorectal cancer.

Detailed description

Based on investigators' experience, compared to robotic-assisted colorectal cancer radical resection, robotic colorectal cancer radical resection with natural orifice extraction has more advantages in postoperative stress response, postoperative pain, postoperative recovery and postoperative abdominal aesthetics. However, in terms of tumor radicality, there may be no obvious differences. There are no randomized controlled trails to discuss these questions.This research is based on the above conditions. Investigators use prospective randomized controlled trial to analyze the surgical data, postoperative complications, postoperative recovery of the robotic colorectal cancer radical resection with natural orifice extraction and conventional robotic-assisted colorectal cancer radical resection in order to summarize clinical experience and explore the advantages and disadvantages of robotic colorectal cancer radical resection with natural orifice specimen extraction and to provide a new direction for the surgical treatment of colorectal cancer, which is beneficial to the promotion of NOSES(Natural Orifice Specimen Extraction Surgery ) technology and treatment of colorectal cancer.

Conditions

• Colorectal Neoplasms
• Neoplasms Malignant
• Complication of Surgical Procedure
• Robotic Surgical Procedures
• Natural Orifice Specimen Extraction Surgery

Interventions

Type	Name	Description
PROCEDURE	Natural Orifice Specimen Extraction Surgery	In the experimental group, patients will be performed robotic colorectal resection with natural orifice specimen extraction.
PROCEDURE	Traditional Robotic-assisted Surgery	In the active comparator group, patients will be performed traditional robotic-assisted colorectal resection.

Timeline

• Start date: 2021-02-01
• Primary completion: 2021-12-31
• Completion: 2022-12-31
• First posted: 2020-01-18
• Last updated: 2020-01-22

Locations

7 sites across 1 country: China