NCT04226586

Nutritional Stimulation of Growth in Children With Short Stature

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Arkansas Children's Hospital Research Institute · Academic / Other
• Sex: All
• Age: 3 Years – 11 Years
• Healthy volunteers: Accepted

Summary

Short stature is a frequent reason for referral to a pediatric endocrinology clinic. Short stature is especially prevalent among those with failure to thrive (whose weight is significantly below the average weight of his/her peers). The growth hormone has limited efficacy for medical treatment of short stature when the cause of short stature is not growth hormone deficiency. This study will investigate the effect of 6 months of nutritional supplement (essential amino acids) compared to placebo in the linear growth of short children who have not yet reached puberty.

Conditions

• Nutritional Stunting
• Growth Failure

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Essential Amino Acid (EAA) group	Eligible children will be supplemented with Essential Amino Acids (EAA) for 6 months twice a day. Caution will be exercised to match the groups for age and sex.
DIETARY_SUPPLEMENT	Placebo	Eligible children will be supplemented with a placebo for 6 months twice a day. Caution will be exercised to match the groups for age and sex.

Timeline

• Start date: 2020-09-09
• Primary completion: 2022-03-15
• Completion: 2022-12-31
• First posted: 2020-01-13
• Last updated: 2024-07-31

Locations

1 site across 1 country: United States