NCT04224532

The Effect of Pneumoperitoneum Timing on Intracranial Pressure in Laparoscopy

The Effect of Pneumoperitoneum Timing on Intracranial Pressure in Laparoscopic Cholecystectomy: Before or After Reverse Trendelenburg Position

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 79 (actual)
• Sponsor: Bagcilar Training and Research Hospital · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Reverse Trendelenburg position has been shown to slightly reduce the intracranial pressure associated with pneumoperitoneum. However, there are no studies on the effect of the timing of reverse Trendelenburg position on intracranial pressure. This study will monitor the effect of reverse Trendelenburg position before or after pneumoperitoneum on intracranial pressure and regional cerebral oxygen saturation.

Detailed description

The literature includes studies that investigate the relationship of pneumoperitoneum and different positions with intracranial pressure during laparoscopy. Reverse Trendelenburg position has been shown to slightly reduce the intracranial pressure associated with pneumoperitoneum. However, there are no studies on the effect of the timing of reverse Trendelenburg position on intracranial pressure. This study will monitor the effect of reverse Trendelenburg position before or after pneumoperitoneum on intracranial pressure and regional cerebral oxygen saturation. Ultrasound guided measurement of the optic nerve sheath diameter as a non-invasive method will be used for measurement. The investigators believe reverse Trendelenburg position before pneumoperitoneum may prevent undesired sudden increases in intracranial pressure.

Conditions

• Intracranial Pressure Increase
• Pneumoperitoneum

Interventions

Type	Name	Description
PROCEDURE	Pneumoperitoneum Timing (Before Positioning)	Before Reverse Trendelenburg Position
PROCEDURE	Pneumoperitoneum Timing (After Positioning)	After Reverse Trendelenburg Position

Timeline

• Start date: 2020-01-08
• Primary completion: 2020-03-01
• Completion: 2020-03-01
• First posted: 2020-01-13
• Last updated: 2020-06-04

Locations

1 site across 1 country: Turkey (Türkiye)