NCT04223323

Effects of Almond Consumption on the Human Gastrointestinal Microbiota and Metabolic Health

SNACKing Study: Effects of Snacking on the Gastrointestinal Microbiota and Metabolism

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of Illinois at Urbana-Champaign · Academic / Other
• Sex: All
• Age: 30 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The proposed work will investigate the effect of almond consumption as a snack on human gastrointestinal microbiota and on metabolic health.

Detailed description

This study is a randomized, controlled, investigator-blinded, parallel arm design with two treatment conditions. There will be a phone screening, in person pre-intervention testing, a one-week baseline period devoid of all nuts and seeds followed by a 12-week intervention period, and a post-testing appointment. Participants will be randomized to consume almonds or isocaloric snack for 12 weeks. Participants will provide stool samples during baseline testing and during the 12th week of the intervention.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Almonds	Participants in the intervention group will consume 2oz of almonds daily over the course of 12 weeks.
DIETARY_SUPPLEMENT	Pretzels	Participants in the control group will consume an isocaloric amount of pretzels daily over the course of 12 weeks.

Timeline

• Start date: 2020-02-10
• Primary completion: 2023-12-20
• Completion: 2023-12-20
• First posted: 2020-01-10
• Last updated: 2024-12-06

Locations

1 site across 1 country: United States