Trials / Active Not Recruiting
Active Not RecruitingNCT04221178
Stopping Maintenance Therapy in People With Multiple Myeloma in MRD-Negative Remission
A Single-Arm, Prospective Study of Maintenance Therapy Cessation for Patients With Multiple Myeloma in Sustained MRD-Negative Remissions
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study will test whether stopping maintenance therapy in people with multiple myeloma in MRD-negative remission has the same effect on disease control as continuing this therapy. The study will look at whether people currently on maintenance therapy can safely stop this treatment and continue with active surveillance instead while keeping their MRD-negative remission status for at least 1 year.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Cessation of continuous matinenace therapy | Cessation of maintenance therapy for participants in sustained MRD-negative remission while under careful observation |
Timeline
- Start date
- 2020-01-03
- Primary completion
- 2027-01-03
- Completion
- 2027-01-03
- First posted
- 2020-01-09
- Last updated
- 2026-02-10
Locations
7 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT04221178. Inclusion in this directory is not an endorsement.