Clinical Trials Directory

Trials / Completed

CompletedNCT04218734

A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM

A Multicenter, Randomized, Double-blind, Parallel Controlled Phase III Clinical Trial of DBRP108 in Combination With Metformin Hydrochloride in the Treatment of Type 2 Diabetes Mellitus

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
214 (actual)
Sponsor
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study aims to evaluate the efficacy and safety of DBPR108 tablets in combination with metformin hydrochloride in the treatment of type 2 diabetes mellitus. A total of 210 subjects will be randomly assigned in a ratio of 2:1 to receive metformin hydrochloride plus DBPR108 or metformin hydrochloride plus placebo.

Conditions

Interventions

TypeNameDescription
DRUGDBPR108DBPR108: 100 mg, once daily for 24 weeks.
DRUGmetformin hydrochloridemetformin hydrochloride: 500 mg, 1-3 times daily for 24 weeks.
DRUGplacepoplacebo:100 mg, once daily for 24 weeks.

Timeline

Start date
2020-01-14
Primary completion
2021-06-03
Completion
2021-06-03
First posted
2020-01-06
Last updated
2021-06-28

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04218734. Inclusion in this directory is not an endorsement.