NCT04217655

Low-dose Computed Tomography-guided Core Needle Biopsy for Lung Nodules

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Xuzhou Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Investigators aim to compare the diagnostic accuracy and radiation exposure between low-dose and standard-dose computed tomography-guided core needle biopsy for lung nodules.

Detailed description

At present, low-dose scanning protocol is widely used in computed tomography-guided interventions because these procedures usually require repeat scans, which causes more radiation exposure to the patients. Computed tomography-guided core needle biopsy is widely used in diagnosis of lung nodules with an overall diagnostic accuracy of 93%-97%. Compared with the large lung lesions, computed tomography-guided core needle biopsy for lung nodules might require more scanning to adjust the position of needle tip. Therefore, it might expose the patients to more radiation. However, studies regarding computed tomography-guided core needle biopsy for lung nodules are still lacking. In this study, investigators aim to compare the diagnostic accuracy and radiation exposure between low-dose and standard-dose computed tomography-guided core needle biopsy for lung nodules.

Conditions

• Lung Cancer
• Lung; Node

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Low-dose computed tomography	Radiation dose under the low-dose protocol computed tomography (120 kilovolt, 15 milliampere seconds)
DIAGNOSTIC_TEST	Standard-dose computed tomography	Radiation dose under the standard-dose protocol computed tomography (120 kilovolt, 150 milliampere seconds)

Timeline

• Start date: 2020-06-01
• Primary completion: 2020-12-31
• Completion: 2021-12-28
• First posted: 2020-01-03
• Last updated: 2021-12-29

Locations

1 site across 1 country: China