Trials / Unknown
UnknownNCT04217265
Letrozole Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
Letrozole Pretreatment With Misoprostol for Induction of Abortion In First-Trimester Missed Miscarriage: A Randomized Controlled Trial
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Cairo University · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study compares the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.
Detailed description
According to the American college of obstetricians and gynecologists (2005), medical abortion is an acceptable alternative for surgical procedures in pregnant women with gestational age of less than 49 days based on the last menstrual period Oral or vaginal misoprostol causes complete abortion in almost 85% of cases within seven days before the 12th week letrozole administration with misoprostol raises the rate of complete abortion
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Letrozole then misoprostol | total dose 5 mg per day for 3 days then Misoprosrol 800mcg will be given to all patients for induction of abortion |
| DRUG | placebo then misoprostol | placebo tablets for 3 days then Misoprosrol 800mcg will be given to all patients for induction of abortion |
Timeline
- Start date
- 2020-01-05
- Primary completion
- 2020-04-05
- Completion
- 2020-04-10
- First posted
- 2020-01-03
- Last updated
- 2020-01-03
Source: ClinicalTrials.gov record NCT04217265. Inclusion in this directory is not an endorsement.