NCT04216836

One Week of Magnesium Supplementation Lowers IL-6, Perceived Pain and Increases Post Exercise Blood Glucose in Response to Downhill Running

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: University of Worcester · Academic / Other
• Sex: Male
• Age: 20 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study investigated the effect of magnesium supplementation on exercise performance and functional recovery in recreational endurance athletes in conjunction with measures of blood glucose, lactate, IL-6 and sIL-6R.

Detailed description

Magnesium status can directly affect circulating glucose concentrations both during and post exercise. In addition, magnesium supplementation has been shown to reduce circulating IL-6 concentrations post exercise in humans. It is conceivable that such observations are linked through the role of IL-6 in glucose regulation, possibly in combination with sIL-6R. Together, magnesium intake may have the potential to effect exercise performance and recovery through glucose availability. This in turn may be connected to the production of IL-6 and sIL-6R which have been established to influence exercise fatigue and perception of pain (muscle soreness).

Conditions

• Magnesium Deficiency

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Magnesium oxide	Magnesium capsule
DIETARY_SUPPLEMENT	Placebo	Cornflour capsule manufactured to mimic the 166.6 mg magnesium capsule.

Timeline

• Start date: 2018-06-28
• Primary completion: 2019-03-01
• Completion: 2019-03-01
• First posted: 2020-01-03
• Last updated: 2020-01-03

Locations

1 site across 1 country: United Kingdom