NCT04216043

Milk Matters in Malnutrition, is it the Lactose or Dairy Protein?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,102 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 6 Months – 59 Months
• Healthy volunteers: Not accepted

Summary

This study is to look at the types of sugar and protein composition in the treatment of moderate acute malnutrition and its effects on gut health. The study will use 4 different types of ready to use supplementary foods to see which one if any has better recovery rate along with looking into the gut health. Children will be treated using one food for up to 12 weeks. A subset of about 400 will be tested for intestinal permeability using the dual sugar test.

Conditions

• Malnutrition, Child

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	RUSF skimmed milk powder	ready-to-use supplementary foods 75 kcal/kg/day (314 kJ/kg/day) and full daily doses of vitamins and micronutrients
DIETARY_SUPPLEMENT	RUSF milk protein concentrate and sucrose	ready-to-use supplementary foods 75 kcal/kg/day (314 kJ/kg/day) and full daily doses of vitamins and micronutrients
DIETARY_SUPPLEMENT	RUSF soy protein and whey permeate	ready-to-use supplementary foods 75 kcal/kg/day (314 kJ/kg/day) and full daily doses of vitamins and micronutrients
DIETARY_SUPPLEMENT	RUSF soy and sucrose	ready-to-use supplementary foods 75 kcal/kg/day (314 kJ/kg/day) and full daily doses of vitamins and micronutrients

Timeline

• Start date: 2020-09-16
• Primary completion: 2022-03-07
• Completion: 2022-03-07
• First posted: 2020-01-02
• Last updated: 2024-01-05

Locations

1 site across 1 country: Sierra Leone