NCT04215913

Integrative Analysis of Pulmonary Sarcomatoid Carcinoma (PSC)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Integrative Analysis of pulmonary sarcomatoid carcinoma (PSC)

Detailed description

The investigators will analyzed proteomes of paired normal lung tissues and pulmonary sarcomatoid carcinoma with or without metastasis, sequenced transcriptomes, perform whole exome sequencing, and single nucleotide polymorphism (SNP) array profiling for triplets, each comprising normal lung tissue, primary pulmonary sarcomatoid carcinoma, and its synchronous matched metastasis, as well as analyzed genomics of lung cancer characterized previously by The Cancer Genome Atlas (TCGA) to conduct integrated proteogenomic analyses.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
OTHER	The investigators will extract total protein, DNA and RNA from PSC patients.	The investigators will extract total protein, DNA and RNA from PSC patients.

Timeline

• Start date: 2019-12-30
• Primary completion: 2025-12-24
• Completion: 2025-12-24
• First posted: 2020-01-02
• Last updated: 2020-01-02

Locations

1 site across 1 country: China