NCT04213287

Multimodal Analgesia Methods in Patients Undergoing IPACK Block in Knee Arthroplasty

Evaluation of Multimodal Analgesia Methods in Patients Who Underwent IPACK Block in Total Knee Arthroplasty

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Ankara Diskapi Training and Research Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

A comparison of two pain control methods - the combination of Adductor Canal Block (ACB)/Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (IPACK) versus the Periarticular Injection (PAI)/ Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (IPACK) - in patients undergoing total knee arthroplasty. dexketoprofen and paracetamol will be added to both groups and multimodal analgesia will be applied. Primary outcome is NRS pain scores with ambulation on postoperative day one (24 hours post-block administration).

Detailed description

Postoperative pain after total knee arthroplasty is serious and difficult to management. Multimodal analgesia recommended for the pain management. For these reasons, we planned a study involving two multimodal analgesia regimens. Patients who will undergo total knee arthroplasty will receive preemptive oral analgesic (dexketofrofen) 1 hour before the operation. Surgery will be initiated after spinal anesthesia is applied to the patients. Two pain control methods - the combination of Adductor Canal Block (ACB)/Infiltration of the interspace between the popliteal artery and the capsule of the posterior knee (IPACK) versus the Periarticular Injection (PAI)/ IPACK- will be applied at the end of the surgery. dexketoprofenand paracetamol will be added to both groups and multimodal analgesia will be applied. Primary outcome is NRS pain scores with ambulation on postoperative day one (24 hours post-block administration).

Conditions

• IPACK Block Multimodal Analgesia
• Postoperative NRS Scores

Interventions

Type	Name	Description
DRUG	Dexketoprofen Trometamol	Drug: Dexketoprofen Trometamol oral tablet
OTHER	spinal anesthesia	Drug: heavy bupivacaine 2,5 ml 0,5%
OTHER	IPACK	Drug: bupivacaine 20 ml 0,025%
OTHER	PAI	Drug: bupivacaine 30 ml 0,025%
OTHER	Adductor canal block	Drug: bupivacaine 20 ml 0,025%

Timeline

• Start date: 2019-12-23
• Primary completion: 2020-03-01
• Completion: 2020-03-15
• First posted: 2019-12-30
• Last updated: 2019-12-30

Locations

1 site across 1 country: Turkey (Türkiye)