Trials / Completed
CompletedNCT04213157
Laparoscopic Partial Nephrectomy for cT1 Tumors
Evaluation Trifecta and Pentafecta Outcomes of Patients Underwent Laparoscopic Partial Nephrectomy for cT1 Renal Tumor
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 292 (actual)
- Sponsor
- Samsun Liv Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 82 Years
- Healthy volunteers
- Not accepted
Summary
The aim of the study is to evaluate trifecta and pentafecta outcomes for laparoscopic partial nephrectomy (LNP) in patients with clinical T1N0M0 renal tumor.
Detailed description
From November 2009 to August 2018 a total of 292 patients who underwent LPN by global ischemia were included in the study. The patients were allocated into two groups according to the tumor size; T1a (≤ 40 mm, n=215), T1b (41-70 mm, n=77). Demographics features, clinical tumor characteristics, intraoperative and postoperative outcomes were analyzed. A negative surgical margin, warm ischemia time (WIT) \< 20 min and no postoperative complications (Clavien-Dindo ≥ grade 3) were accepted to achieve the trifecta outcomes. Pentafecta has defined as trifecta criteria plus \>90% preservation of estimated glomerular filtration rate (eGFR) and no stage upgrade of chronic kidney disease 12 months after LPN. Univariable and multivariable analysis were used to identify factors predicting trifecta and pentafecta achievement.
Conditions
- Renal Cancer
- Renal Neoplasm
- Renal Cell Carcinoma
- Surgery
- Surgery--Complications
- Renal Functional Abnormality
- Oncology
- Oncology Problem
- Kidney Ischemia
- Kidney Injury
- Urologic Neoplasms
- Urologic Cancer
- Kidney Neoplasms
Timeline
- Start date
- 2019-03-15
- Primary completion
- 2019-08-30
- Completion
- 2019-11-10
- First posted
- 2019-12-30
- Last updated
- 2020-01-02
Locations
2 sites across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT04213157. Inclusion in this directory is not an endorsement.